Which type of tissue would have a higher mitotic index. Which type of tissue would have a higher mitotic index... Free Essays 2022-12-20
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The mitotic index is a measure of how actively cells in a tissue are dividing. It is calculated by counting the number of cells in a tissue that are in the process of mitosis (cell division) and dividing by the total number of cells in the tissue. A higher mitotic index means that more cells in the tissue are actively dividing, while a lower mitotic index indicates that fewer cells are dividing.
There are several factors that can influence the mitotic index of a tissue. One of the most important factors is the rate of cell growth and repair in the tissue. Tissues that are actively growing or repairing themselves, such as the lining of the intestine or the bone marrow, will typically have a higher mitotic index. This is because these tissues need to constantly produce new cells to replace damaged or lost cells.
Other factors that can affect the mitotic index of a tissue include hormones, environmental factors, and disease. For example, certain hormones, such as thyroid hormone and growth hormone, can stimulate cell division and increase the mitotic index. Environmental factors, such as exposure to radiation or certain chemicals, can also affect the mitotic index by promoting or inhibiting cell division. Finally, certain diseases, such as cancer, can also increase the mitotic index by causing abnormal and uncontrolled cell division.
In summary, tissues that are actively growing or repairing themselves, or that are influenced by hormones, environmental factors, or disease, are likely to have a higher mitotic index. This includes tissues such as the lining of the intestine, the bone marrow, and certain cancerous tissues.
Which type of tissue would have a higher mitotic index... Free Essays
Mitotic rate: What is the normal range? Which tissue has the greatest rate of cell division? Cancerous cells has high ability to divide continuously and requires less nutrient factors. In that case, one dose higher and two doses lower that that target dose should be selected to ensure the appropriate range of toxicity is covered and should include one nontoxic dose. The cutaneous membrane is composed of keratinizing stratified squamous epithelium. In the absence of any substantial reduction in the density of mitotic figures, the highest dose chosen for each treatment regimen should be the lowest precipitating concentration or, in the absence of precipitate, the highest dose level tested. So, skin exhibits the highest mitotic index. Conective tissues are cells that are suspended in a matrix of their own secretions Premium Tissues Connective tissue Stomach Epithelial tissue types layers upon a basal membrane.
This is positioned immediately to the left of creatine Cr , which has a peak at 3. In addition, it is felt that membrane bound molecules can play a role in the regulation of signal transduction pathways Fig. B Stratified epithelia are Premium Epithelium Tissues Connective tissue Plant Tissues BIO - PROJECT PLANT TISSUES Two Major Categories of Plant Tissues 1. Epithelial tissue covers the whole surface of the body. The steps were optimized using Imaris Bitplane for retinal epithelium and might need to be modified for analysis of mitotic index in other tissues. The skin forms the outer most covering of the body surface.
When studying cell division in tissue samples, scientists often calculate a mitotic index, which is
What is considered a high mitotic index? There will be fewer cells in mitosis as a percentage of total cells decreases, resulting in a decrease in the mitotic index. How is the mitotic index of a cell calculated? Another published study using cisplatin, etoposide, vincristine, cyclophosphamide, and carboplatin reduces the cisplatin and vincristine doses by 50% and the incidence of significant ototoxicity and neuropathy see Table 22. When toxicity is seen, the highest test substance dose chosen for detailed examination should show approximately 50% reduction in the MI when compared to the vehicle. Instead of dying, these aberrant cells continue to grow and replicate. Explanation: Mitotic index may be defined as the cells that undergoes mitosis by the total number of cells.
Is the mitotic index of a population of cells that lose the capacity to divide as they age expected to change? Robert McCauley, in Total Burn Care Fourth Edition , 2012 Molecular basis of tissue expansion Clearly, several studies have documented an increased mitotic index in the epidermis with tissue expansion. Are there any safety concerns associated with this exercise? Occur near tips of roots and shoots b. Which cells undergo mitosis at a rapid rate? Fundamental Tissue Ground Tissue C. Mitosis occurs rapidly in the growing regions, the dermis of the skin, where cells are replaced continuously, the region of wound healing, etc. Details of toxicokinetic and preliminary investigations if performed , mortalities and clinical signs, and any other assessments of toxicity made should be reported and, when appropriate, presented in tabular form in the study report. NAA, a marker of intact neurons, will be depressed in many disease processes, including in some oligodendrogliomas and other primary brain tumors. In cancer cells, the mitotic index may be elevated compared to normal growth of tissues or cellular repair of the site of an injury.
In this way, the mitotic index is determined for the full volume of the whole tissue. The N—CH 3 group of Cho, the first major peak from the left on MRS, has a resonance at 3. I learned that cancerdevelops when cells in a part of the body begin to grow out of control. Where does mitosis occur most in the human body? Nu 20 per roll both kitchen roll and toilet roll and Nu. Exercise 1: Epithelial Tissue Data Table 1: Epithelial Tissue Observations TISSUE TYPE OBSERVATIONS Simple Squamous Simple Cuboidal Simple Columnar stomach Premium Tissues Muscle Connective tissue Tissues and Membranes PHYSIOLOGY I Chapter 4: TISSUES AND MEMBRANES Outline of Notes I.
Which type of tissue would have a higher mitotic index? (a) Cancerous ovarian tissue (b) Normal ovarian tissue (c) Both (a) and (b) (d) Neither (a) or (b), the mitotic index cannot be calculated for ovarian tissue.
From my data i can determine the cancer cells have a higher mitotic index. What does mitotic stand for? In patients who have high-risk disease Table 21-8 adjuvant chemotherapy in combination with 36Gy craniospinal radiation improves the disease-free survival for medulloblastoma. What does it mean when mitotic activity increases? In a population of cells, the ratio of the number of cells undergoing mitosis cell division to the number of cells not undergoing mitosis. What does an elevated mitotic index in cancer mean? Thus, information about the existence and distribution of hubs of proliferation, could, theoretically, be gathered. The Pediatric Oncology Group study A9961 utilizing reduced dose CSI of 23.
Which normal tissues would have the highest mitotic index?
This enables the creation of an image mask. This could be done as an additional sequence after the standard high TE sequence, if time permits. If there is no evidence for a difference in response between the sexes in terms of structural aberrations, then the results may be combined to maximize the power of statistical analysis. A detailed understanding of tissues will greatly help your understanding of organs and organ systems later in this course. Cancer tissue generally has more mitotic activity than normal tissues. This group postulated that platelet-derived growth factor PDGF , as well as other growth factors, could stimulate cutaneous cells.
Name the three subtypes of muscle tissue. This prevents it from collapse Premium Epithelium Respiratory system Connective tissue. This left frontal infiltrating tumor shows moderate depression of NAA as the only abnormality of the three major peaks B, arrowheads. The secretory cells fragment and are lost in the secretion; thus the secretory cells must be continuously replaced. Note decrease in NAA levels in this image, higher concentrations are red, lower are blue or green; the arrow points to a predominantly blue and green region in the left frontal lobe approximately corresponding to the area of increased signal on FLAIR A. It is possible for cancer cells to have a high mitotic index relative to normal tissue development or cellular repair.
Which type of tissue has a higher mitotic index normal or cancerous? Conclusion Cancer cells divide more rapidly than normal cells. The adjacent two lower dose levels should also be selected for detailed examination. Different types of structural chromosomal aberrations should be listed with their numbers and frequencies. I also learned that during the early years of a person's life, normal cells divide more rapidly until the person becomes an adult. The Children's Oncology Group study utilizing craniospinal irradiation following surgery and adjuvant CCNU, vincristine and cisplatinum Table 21-4 chemotherapy has demonstrated an 89% progression-free survival rate in nondisseminated posterior fossa medulloblastoma with decreased craniospinal irradiation. Sometimes, however, MRS is nondiagnostic owing to the proximity of the cavity and magnetic field heterogeneity caused by blood degradation products and other contents of the cavity. A is usually acellular B contains a number of neuron types C is highly vascularized D has a basement membrane 2.
(Solved) Which type of tissue would have a higher mitotic index?
If routine follow-up MRI shows growth of the area of abnormal signal, MRS can be used to attempt to distinguish incidental postoperative gliosis or signal changes related to RT from those changes related to tumor progression. An elevated mitotic index indicates more cells are dividing. APICAL MERISTEMS Primary Growth 1. Mitotic Activity Index MAI is an essential prognostic indicator and a key component of the grading system for breast cancer, both alone and collectively. Mitotic cells can be detected as spots or particles in the masked image automatically from the pH3 channel Fig. It is made up of cells closely packed and ranged in one or more layers.
